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2183 SARS-CoV-2 Rapid Antigen Testphs002682N/A488Medical Device or Tool Development; Point-of-Care (POC) Testing; Rapid Diagnostic Test (RDT)Device ValidationAntigen Testing Device; SurveyNIBIBRADx TechYes
A Community Health Worker Intervention to Identify and Decrease Barriers to Pre-Procedural COVID-19 Testing Among Los Angeles County Department of Health Safety-Net Patientsphs002920Adults; Older Adults or Elderly; Hispanics or Latinos; Racial or Ethnic Minorities; Underserved or Vulnerable Populations; African Americans46Testing Rate or Uptake; Vaccination Rate or Uptake; Pandemic Perceptions or Decision-Making; Virological TestingInterventional or Clinical TrialSurvey; Interview or Focus GroupNLMRADx-UPYes
A Community-Led Approach to Enhance COVID-19 Testing Among Vulnerable Latinosphs002660Older Adults or Elderly; Hispanics or Latinos; Adults4312Social Determinants of Health; Diagnostic TestingLongitudinal CohortInterview or Focus Group; SurveyNIDARADx-UPYes
A Confectionary-Based Screening Tool for Assessing Chemosensory Loss in COVID-19 Patientsphs002642Adults1059Rapid Diagnostic Test (RDT); Medical Device or Tool DevelopmentLongitudinal CohortChemosensory Testing DeviceNIDCDRADx-radYes
A Data Science Approach to Identify and Manage Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection and Kawasaki Disease in Pediatric Patientsphs002945Children944Multisystem Inflammatory Syndrome in Children (MIS-C); Artificial Intelligence or Machine Learning; Multisystem Inflammatory Syndrome (MIS)Cross-SectionalDisease RegistryNICHDRADx-radYes
A Dynamic COVID-19 Community-Engaged Testing Strategy in Alabama (COVID COMET AL)phs002871Rural Communities; Adults; Children; Older Adults or Elderly; Underserved or Vulnerable Populations; Incarcerated or Institutionalized Populations24082Social Determinants of HealthCross-SectionalMolecular Nucleic Acid or PCR Testing Device; Survey; Interview or Focus GroupNIAIDRADx-UPYes
A Handheld Microchip for GC Analysis of Breath to Screen for COVID-19phs002563N/A42Rapid Diagnostic Test (RDT); Medical Device or Tool Development; Virological Testing; Artificial Intelligence or Machine Learning; Novel Biosensing or VOCLongitudinal CohortBreath Analysis or Airborne Detection DeviceNCATSRADx-radYes
A Multimodal Platform for Oral Screening of COVID-19phs002570N/A12Multimodal Surveillance; Novel Biosensing or VOC; Virological Testing; Rapid Diagnostic Test (RDT); Medical Device or Tool DevelopmentDevice VerificationElectrochemical Testing DeviceNIDCRRADx-radYes
A Nurse-Community Health Worker-Family Partnership Model: Addressing Uptake of COVID-19 Testing and Control Measuresphs002906Hispanics or Latinos; Lower Socioeconomic Status (SES) Populations; Older Adults or Elderly; Adults; Underserved or Vulnerable Populations; Racial or Ethnic Minorities; African Americans398Diagnostic Testing; Testing Rate or Uptake; Community Outreach Programs; Social Determinants of HealthCase-ControlSurveyNIDARADx-UPYes
A Rapid Breathalyzer Diagnostics Platform for COVID-19phs002583Adults0Novel Biosensing or VOC; Medical Device or Tool Development; Virological Testing; Rapid Diagnostic Test (RDT)Device VerificationBreath Analysis or Airborne Detection Device; Antigen Testing DeviceNHLBIRADx-radYes
A Rapid Saliva Antigen Test for SARS-CoV-2 Detectionphs002689N/A60Novel Biosensing or VOC; Medical Device or Tool Development; Rapid Diagnostic Test (RDT)Longitudinal CohortAntigen Testing DeviceNHLBIRADx-radYes
A Rapid, Sensitive, Point-of-Care, Antigen-Based Diagnostics for SARS-CoV-2phs002561N/A15Rapid Diagnostic Test (RDT); Novel Biosensing or VOC; Medical Device or Tool DevelopmentDevice ValidationAntigen Testing DeviceNHLBIRADx-radYes
A SARS-CoV-2 Breathalyzer for Direct Virus Detectionphs002572N/A0Medical Device or Tool Development; Novel Biosensing or VOC; Virological Testing; Multimodal SurveillanceDevice ValidationUnspecified COVID Testing DeviceNIDCRRADx-radNo
A Scalable Aptamer-Based Electrochemical Biosensor for Rapid Detection of SARS-CoV-2 from Salivaphs002702N/A0Medical Device or Tool Development; Novel Biosensing or VOC; Virological TestingDevice VerificationUnspecified COVID Testing DeviceNIDCRRADx-radNo
AFS/SERS Saliva-Based SARS-CoV-2 Earliest Infection and Antibodies Detectionphs002544N/A478Virological Testing; Medical Device or Tool DevelopmentDevice ValidationMolecular Nucleic Acid or PCR Testing DeviceNCATSRADx-radYes
AICORE-kids: Artificial Intelligence COVID-19 Risk AssEssment for kidsphs002585Children77607Artificial Intelligence or Machine Learning; Social Determinants of HealthLongitudinal CohortReal-World DataNICHDRADx-radYes
Accurate, Sensitive and Affordable POC and At Home Testing Devicephs002737Older Adults or Elderly; Adults; Children285Medical Device or Tool Development; Point-of-Care (POC) TestingDevice ValidationSmartphone; Molecular Nucleic Acid or PCR Testing Device; SurveyNHLBIRADx TechYes
Adapting Community-Based Task-Shifting for the COVID-19 Response Among Underserved Populations in Piedmont, North Carolina (ACT UP)phs002581Essential Workers; Adults; Underserved or Vulnerable Populations; Racial or Ethnic Minorities; Hispanics or Latinos; African Americans; Older Adults or Elderly; Rural Communities; Immigrants665Vaccination Rate or Uptake; Community Outreach Programs; Virological Testing; Testing Rate or UptakeLongitudinal CohortSurvey; Interview or Focus GroupNIAIDRADx-UPYes
Addressing COVID-19 Testing Disparities in Vulnerable Populations Using a Community JITAI (Just in Time Adaptive Intervention) Approach-A UTHealth CTSA Programphs002761African Americans; Racial or Ethnic Minorities; Hispanics or Latinos; Homeless or Unhoused Populations; Adults; Underserved or Vulnerable Populations; Older Adults or Elderly1551Community Outreach Programs; Testing Rate or Uptake; Virological Testing; Comorbidities; COVID Hotspots; COVID Testing DesertsCross-SectionalSurveyNCATSRADx-UPYes
Addressing COVID-19 Testing Disparities in Vulnerable Populations Using a Community JITAI (Just in Time Adaptive Intervention) Approach: RADx-UP Phase IIIphs003687Adults; Underserved or Vulnerable Populations; Hispanics or Latinos; African Americans; Rural Communities; Older Adults or Elderly781Community Outreach Programs; Disease Surveillance; Social Determinants of HealthInterventional or Clinical TrialSurveyNCATSRADx-UPYes
Addressing Low-Income Housing Resident Mistrust in COVID-19 Guidancephs002743Lower Socioeconomic Status (SES) Populations; Adults; Older Adults or Elderly54Social Determinants of Health; Pandemic Perceptions or Decision-Making; Vaccination Rate or Uptake; Testing Rate or UptakeLongitudinal CohortSurvey; Interview or Focus GroupNCIRADx-UPYes
Alive Church Network: Increasing COVID-19 Testing in Chicago's African American Testing Desertsphs002645African Americans; Underserved or Vulnerable Populations; Children; Adults; Older Adults or Elderly1770Community Outreach Programs; Rapid Diagnostic Test (RDT); Testing Rate or UptakeTime-SeriesSurvey; Molecular Nucleic Acid or PCR Testing DeviceNINRRADx-UPYes
An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetesphs003864African Americans; Hispanics or Latinos; Underserved or Vulnerable Populations; Lower Socioeconomic Status (SES) Populations286Testing Rate or Uptake; Vaccination Rate or Uptake; Comorbidities; At-Home or Over-the-Counter (OTC) Self-TestingMixed MethodsInterview or Focus Group; SurveyNIDDKRADx-UPYes
Assessing Testing Strategies for Safe Return to K-12 Schools in an Underserved Populationphs002759School Communities; Children; Underserved or Vulnerable Populations; Adults; Older Adults or Elderly; Children; African Americans1038Social Determinants of Health; COVID in School Settings; Pandemic Perceptions or Decision-Making; Screening TestingCase-ControlInterview or Focus Group; Survey; Molecular Nucleic Acid or PCR Testing DeviceNICHDRADx-UPYes
Assessing Vaccine Hesitancy and a Pharmacist Led Intervention Model to Increase COVID-19 Vaccine Uptake Among African Americansphs002875Adults; African Americans; Essential Workers; Underserved or Vulnerable Populations; Older Adults or Elderly487Health Behaviors; Pandemic Perceptions or Decision-Making; Vaccination Rate or UptakeLongitudinal CohortSurvey; Interview or Focus GroupNIMHDRADx-UPYes
Back to ECE Safely with SAGE: Reducing COVID-19 Transmission in Hispanic and Low-Income Preschoolersphs002661Hispanics or Latinos; Children; School Communities756COVID in School SettingsLongitudinal CohortSurveyNICHDRADx-UPYes
Bioinformatics Framework for Wastewater-based Surveillance of Infectious Diseasesphs002527N/A0Screening Testing; Next Generation Sequencing (NGS); Wastewater SurveillanceObservationalWastewater SamplingNLMRADx-radYes
Bridging the Evidence-to-Practice Gap: Evaluating Practice Facilitation as a Strategy to Accelerate Translation of a Systems-Level Adherence Intervention into Safety Net Practices/Project Evidencephs002616Older Adults or Elderly; Lower Socioeconomic Status (SES) Populations; Racial or Ethnic Minorities; African Americans; Hispanics or Latinos; Adults137Health Behaviors; Testing Rate or Uptake; Vaccination Rate or Uptake; Pandemic Perceptions or Decision-Making; Social Determinants of HealthCross-SectionalInterview or Focus Group; Molecular Nucleic Acid or PCR Testing Device; SurveyNIMHDRADx-UPYes
Broad-Spectrum Detection of VOC and Non-VOC Biomarkers from Patient Exhalant Using a Biomimetic Multiplexed eNose Biosensor for COVID-19 Diagnosisphs002924Adults0Virological Testing; Novel Biosensing or VOC; Artificial Intelligence or Machine Learning; Biosensor TechnologiesLongitudinal CohortBreath Analysis or Airborne Detection DeviceNHLBIRADx-radYes
Building Resiliency and Vital Equity (BRAVE)phs002650Racial or Ethnic Minorities; Underserved or Vulnerable Populations1175Vaccination Rate or Uptake; Social Determinants of Health; Pandemic Perceptions or Decision-Making; Testing Rate or UptakeInterventional or Clinical TrialSurvey; Interview or Focus GroupNIMHDRADx-UPYes
C2SPARC: Implementing Mobile, POC COVID-19 Testing in Partnership with a Community-Based Organization to Reach Women Who Use Drugsphs003123Underserved or Vulnerable Populations; Adults; Older Adults or Elderly; Lower Socioeconomic Status (SES) Populations145Testing Rate or Uptake; Social Determinants of Health; Substance Use; Mobile Unit Testing; Rapid Diagnostic Test (RDT); Point-of-Care (POC) TestingLongitudinal CohortInterview or Focus Group; Antigen Testing Device; SurveyNIDARADx-UPYes
CO-CREATE-Ex: Community-engaged Optimization of COVID-19 Rapid Evaluation And TEsting Experiencesphs003686Children; Immigrants; Underserved or Vulnerable Populations; Adults; Hispanics or Latinos; Older Adults or Elderly6350At-Home or Over-the-Counter (OTC) Self-Testing; Testing Rate or Uptake; Diagnostic Testing; Community Outreach ProgramsLongitudinal CohortSurveyNIMHDRADx-UPYes
COVID Self-Testing Through Rapid Network Distribution (C-STRAND)phs002760People Living with HIV/AIDS; Immigrants; Homeless or Unhoused Populations; Older Adults or Elderly; Asians; Hispanics or Latinos; African Americans; Racial or Ethnic Minorities; Adults; Lower Socioeconomic Status (SES) Populations917Substance Use; Community Outreach Programs; Comorbidities; At-Home or Over-the-Counter (OTC) Self-Testing; Testing Rate or UptakeInterventional or Clinical TrialSurvey; Antigen Testing Device; Interview or Focus GroupNHLBIRADx-UPYes
COVID-19 Detection through Scent Analysis with a Compact Gas Chromatography Devicephs002747N/A52Novel Biosensing or VOC; Medical Device or Tool Development; Virological TestingCase-ControlBreath Analysis or Airborne Detection DeviceNCATSRADx-radYes
COVID-19 Experience Study (C19EX) Surveyphs002537Adults36561Digital Health Applications; Biosensor Technologies; Artificial Intelligence or Machine LearningLongitudinal CohortSurveyNCIRADx DHTNo
COVID-19 Large Network Centerphs002643Underserved or Vulnerable Populations; Older Adults or Elderly; Adults; Racial or Ethnic Minorities6282Social Determinants of Health; Testing Rate or Uptake; Community Outreach ProgramsLongitudinal CohortContact Tracing; SurveyNCATSRADx-UPYes
COVID-19 Network of Networks Expanding Clinical and Translational Approaches to Predict Severe Illness in Children (CONNECT to Predict SIck Children)phs002569Children; Underserved or Vulnerable Populations266Artificial Intelligence or Machine LearningCase-ControlSurveyNICHDRADx-radYes
COVID-19 Test At Home Efficacy Sub-Studyphs003026Older Adults or Elderly; Adults200Medical Device or Tool Development; At-Home or Over-the-Counter (OTC) Self-TestingLongitudinal CohortAntigen Testing Device; Molecular Nucleic Acid or PCR Testing Device; SmartphoneNHLBIRADx TechYes
COVID-19 Test At Home Feasibility Sub-Studyphs002739Older Adults or Elderly; Adults206At-Home or Over-the-Counter (OTC) Self-Testing; Medical Device or Tool Development; Digital Health Applications; Virological Testing; Rapid Diagnostic Test (RDT)Longitudinal CohortAntigen Testing Device; SmartphoneNHLBIRADx TechYes
COVID-19 Testing and Linkage to Care with African American Church and Health Agency Partnersphs002578Racial or Ethnic Minorities; African Americans; Adults1102Community Outreach Programs; Health Behaviors; Pandemic Perceptions or Decision-Making; Testing Rate or Uptake; Virological TestingInterventional or Clinical TrialSurvey; Contact TracingNIDDKRADx-UPYes
COVID-19 Testing and Prevention in Correctional Settingsphs003361Incarcerated or Institutionalized Populations; Adults; Underserved or Vulnerable Populations16445Vaccination Rate or Uptake; Social Determinants of Health; Community Outreach Programs; Testing Rate or Uptake; Virological TestingMixed MethodsSurvey; Interview or Focus Group; Contact TracingNIDARADx-UPYes
COVID-19 Testing and Vaccination Social Network Diffusion for Diverse Criminal Legal Involved Communitiesphs003234Adults; Incarcerated or Institutionalized Populations; Underserved or Vulnerable Populations; Older Adults or Elderly858Virological Testing; Pandemic Perceptions or Decision-Making; Testing Rate or Uptake; Vaccination Rate or Uptake; Health BehaviorsInterventional or Clinical TrialSurveyNIMHDRADx-UPYes
COVID-19 Testing in Underserved and Vulnerable Populations Receiving Care in San Diego Community Health Centersphs002869Lower Socioeconomic Status (SES) Populations; Hispanics or Latinos; Older Adults or Elderly; Underserved or Vulnerable Populations; Adults; Children1778Testing Rate or Uptake; Social Determinants of Health; Influenza; Diagnostic TestingInterventional or Clinical TrialSurveyNCIRADx-UPYes
COVID-19 Treatment Cascade Optimization Studyphs002634Adults; Underserved or Vulnerable Populations; Older Adults or Elderly1403Virological Testing; Testing Rate or Uptake; Health BehaviorsInterventional or Clinical TrialInterview or Focus Group; SurveyNIAID; NIMHDRADx-UPYes
COVID-19: Implementing Community-Based Approaches to Increase SARS-CoV-2 Testing Among an Underserved and Vulnerable Hispanic Populationphs002874Hispanics or Latinos; Adults; Rural Communities; Racial or Ethnic Minorities; Underserved or Vulnerable Populations; Older Adults or Elderly3220Social Determinants of Health; COVID Testing Deserts; Testing Rate or Uptake; Mobile Unit Testing; Vaccination Rate or UptakeCross-SectionalSurveyNIMHDRADx-UPYes
Characterization of Multisystem Inflammatory Syndrome in Children and Its Relationship to Kawasaki Diseasephs002553Children264Multisystem Inflammatory Syndrome in Children (MIS-C); Medical Device or Tool Development; Virological Testing; Multisystem Inflammatory Syndrome (MIS)Device ValidationBiobank SamplesNICHDRADx-radYes
Collaborative Community Networks to Optimize Implementation of Low Barrier COVID-19 Testing Efforts Among Diverse Latinx Populations in Northern Californiaphs003375Underserved or Vulnerable Populations; Rural Communities; Older Adults or Elderly; Adults; Children; Racial or Ethnic Minorities; Hispanics or Latinos7942Testing Rate or Uptake; Community Outreach Programs; Virological TestingCross-SectionalSurvey; Molecular Nucleic Acid or PCR Testing DeviceNIAIDRADx-UPYes
Communities Fighting COVID!phs002649Racial or Ethnic Minorities; Older Adults or Elderly; Children; Adults; African Americans; Hispanics or Latinos19161Mobile Unit Testing; At-Home or Over-the-Counter (OTC) Self-Testing; Testing Rate or Uptake; Community Outreach ProgramsCross-SectionalAntigen Testing Device; Contact Tracing; SurveyNCIRADx-UPYes
Communities Fighting COVID!: Returning Our Kids Back to School Safelyphs002878Older Adults or Elderly; Hispanics or Latinos; Racial or Ethnic Minorities; Underserved or Vulnerable Populations; School Communities; Lower Socioeconomic Status (SES) Populations; Adults; Children5045COVID in School Settings; Screening Testing; Rapid Diagnostic Test (RDT); At-Home or Over-the-Counter (OTC) Self-TestingInterventional or Clinical TrialAntigen Testing Device; SurveyNICHDRADx-UPYes
Community Activation to TrAnsform Local sYSTems (CATALYST)phs003377Underserved or Vulnerable Populations; Essential Workers; Adults; Older Adults or Elderly123Community Outreach ProgramsCross-SectionalInterview or Focus Group; SurveyNIMHDRADx-UPYes
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