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Secondary Analysis Spotlight: Leveraging the Data Hub for Health Equity Research with Dr. Amanda Janitz | 09/04/2025

The Data Hub empowers researchers to discover, access, and analyze datasets for secondary use by providing access to de-identified data and cloud-based tools. By streamlining access to valuable research resources, the Data Hub accelerates scientific discovery while maximizing the utility of existing data. Secondary analysis, with the help of the Hub, enables researchers to generate new knowledge, test innovative hypotheses, answer research questions, and advance their fields without the time and resource constraints of primary data collection.

Dr. Amanda Janitz's recent work exemplifies secondary analysis use and potential. Dr. Janitz utilized RADx-UP data and the Data Hub to identify challenges to healthcare access among American Indian/Alaska Native (AI/AN) populations with chronic health conditions. She was awarded the NIH's Exploratory/Developmental Grant (R21).

Results from her study, Challenges Faced by American Indian Population Compared to White Population in Chronic Illness Treatment, were presented at the 2025 Graduate Research Education and Technology (GREAT) Symposium at the University of Oklahoma Health Sciences Center (OUHSC).

Initial analyses showed that AI/AN participants had a higher prevalence of challenges in getting medications, transportation, and getting needed healthcare compared to White participants. Findings like these are important and may contribute to new public health strategies, strengthening health system preparedness. Dr. Janitz and her team are continuing to analyze these data to evaluate challenges accessing healthcare among AI/AN participants with specific chronic health conditions.

This research demonstrates the Data Hub's mission to help researchers discover, access, and analyze data that lead to discoveries. By providing access to rich datasets and powerful analytical tools, the Data Hub enables researchers to focus their energy on generating insights. Data within the Hub is always de-identified and robust enough to facilitate efficient exploration of new research questions. Dr. Janitz’s work highlights the power of secondary research, enabling researchers to develop equitable and impactful public health solutions.

Learn more about Dr. Janitz
Secondary Analysis Spotlight: Culturally Responsive Disease Prevention with Dr. Stephanie De Anda and Dr. Elizabeth Budd | 09/04/2025

The Data Hub is a repository of de-identified data and cloud-based tools enabling researchers to discover, access, and analyze data for secondary use, improving research speed and ease. Secondary analysis is valuable, letting researchers make new discoveries while preserving valuable resources. Through secondary analysis, researchers can generate new knowledge, test hypotheses, and make significant contributions to their field.
Secondary analysis is critical to public health research, and Dr. Stephanie De Anda’s and Dr. Elizabeth Budd’s recent work exemplifies its impact. Dr. De Anda and Dr. Budd were awarded an NIH Exploratory/Developmental Grant (R21) to study vaccine attitudes and access among Latinx communities. Drawing on RADx-UP data housed in the Data Hub, they directly compared social determinants of health (SDOH) and evaluated their relative importance on vaccine outcomes among Latinos to inform future public health efforts.

This secondary research was documented in a recent study and publication, Social determinants of health and COVID-19 vaccination: An individual participant data meta-analysis of adult Latino participants in Preventative Medicine. The authors innovatively directly compared education, economic insecurity, and healthcare access-related SDOH in a single model within a meta sample of only Latinos, created by pooling 12 study samples. Results showed that several factors contributed to vaccination outcomes, including pandemic wave, education, and home Spanish usage.

This research provides evidence that addressing concerns and promoting vaccination confidence early in a pandemic are beneficial. Their research also supports the importance of accessible language communication, especially in communities with lower education levels. These findings are meaningful, because they not only acknowledge social and cultural factors that influence health outcomes and disparities, but also help inform and support culturally responsive strategies for disease prevention and health engagement.

Dr. De Anda and Dr. Budd also presented their research at the Society for Prevention Research Annual Meeting in May 2025 and are scheduled to present again at the American Public Health Association’s Annual Meeting and Expo in November 2025.

Through the Data Hub, researchers like Dr. De Anda and Dr. Budd can collaborate and transform existing data into meaningful progress. Their work highlights the power of secondary research in driving forward equitable and impactful public health solutions.

● Read the article here
Learn more about Dr. De Anda
Learn more about Dr. Budd
Unlock the Power of the RADx Data Hub with Curated YouTube Playlists | 10/25/2024

Are you ready to harness the full potential of the RADx Data Hub? The RADx Data Hub Partners curated multiple YouTube playlists to guide users through this powerful platform....
NIH RADx Data Hub announces major functionality and design upgrades | 05/21/2024

The National Institutes of Health (NIH) Rapid Acceleration of Diagnostics Data Hub (RADx® Data Hub) announces today major functionality and design upgrades to its cloud-enabled platform. These upgrades will provide researchers more dynamic access to explore data from over 150 studies from RADx-rad, RADx-UP, RADx Tech, and RADx DHT programs. Researchers will also be gaining access to an even more robust analytics platform with tools such as Jupyter notebooks, R, Python, and SAS Viya....