dbGaP Study Accession: phs003864

NIH Institute/Center: NIDDK

RADx Data Program: RADx-UP

Release Date: 03/28/2025

Study Description: This multi-institution team (Emory University, Morehouse School of Medicine, Georgia Institute of Technology), anchored by the Georgia Center for Diabetes Translation Research (P30DK111024) partnership, leveraged and expanded on the RADx-UP funded Project PEACH (P30DK111024), to design and evaluate a home-based COVID-19 testing program with behavioral nudges delivered via mobile phone texts to increase uptake of COVID-19 prevention activities (testing, vaccination, preventive behaviors) in “An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetes.” COVID-19 testing remains a cornerstone in understanding and managing the COVID-19 pandemic. The state of Georgia faced several challenges to COVID-19 management including low vaccine rates, over-extended community health partners struggling to manage both COVID-19 testing and vaccination, decreasing COVID-19 testing numbers, and large populations at elevated risk, including those with or at risk for diabetes, individuals at lower socioeconomic levels, and African American/Black and LatinX communities. Project PEACH2 leveraged and expanded on the community partnerships developed as part of Project PEACH to gather additional information on COVID-19 testing, with a particular focus on at-home testing solutions (Aim 1), using both quantitative (an expansion of the follow-up surveys conducted as part of Project PEACH) and qualitative (in-depth interviews with 100 community members, key stakeholders, and community partners) methods. This data, along with the findings of Project PEACH and Georgia CEAL (1OT2HL156812-01/16-312-0217571-66105L), was used to develop text message behavioral nudges to promote continued COVID-19 testing, reporting and preventive behaviors including vaccination targeted to participants’ race/ethnicity, sex, age, vaccination status, and testing history. This study evaluated (Aim 2a) the uptake, usage, and views of a home testing platform (provision a single home COVID-19 test kit for each household family member, collection of test results via an online reporting system, and targeted behavioral nudges delivered via text messages) in a randomized community-based, adaptive intervention trial (n=600) targeting individuals affected by diabetes through collaborations with community partner sites (faith- and community-based organization, the Grady Diabetes Clinic, COVID-19 community testing and vaccine distribution sites). This study also assessed (Aim 2b) how the home testing platform affects vaccine uptake and hesitancy among study participants and family members. This study builds on the successful community-academic partnerships created through Project PEACH to further promote COVID-19 testing among the most vulnerable communities in Georgia. Lessons learned can be disseminated to other at-risk communities and can be adapted to promote home-based testing for other conditions.

Principal Investigator: Weber, Mary Beth

Has Data Files: Yes

Study Domain: At-Home or Over-the-Counter (OTC) Self-Testing; Comorbidities; Testing Rate or Uptake; Vaccination Rate or Uptake

Data Collection Method: Interview or Focus Group; Survey

Keywords: Behavioral Nudges; Community-Academic Partnership; Diabetes; Diabetic Patients

Study Design: Mixed Methods

Multi-Center Study: Yes

Study Sites: Georgia Institute of Technology, Morehouse School of Medicine

Data Types: Behavioral; Clinical; Family History; Questionnaire or Survey; Social

Study Start Date: 01/07/2022

Study End Date: 12/31/2023

Species: Human

Estimated Cohort Size: 600

Study Population Focus: African Americans; Hispanics or Latinos; Lower Socioeconomic Status (SES) Populations; Underserved or Vulnerable Populations

Acknowledgement Statement: This study was supported through funding, 5U01DK132737-02, for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as part of the RADx-UP program. We would like to thank the Georgia Diabetes Translation Research Center (GDTRC), Morehouse School of Medicine’s National Infrastructure for Mitigating the Impact of COVID-19 within Racial and Ethnic Minority Communities (NIMIC), Morehouse School of Medicine’s Prevention Research Center (PRC), Georgia CTSA, Emory Healthcare, Grady Health, and the Georgia Federally Qualified Health Center network. Approved users should acknowledge the provision of data access by dbGaP for accession phs003864.v1.p1, and the NIH RADx Data Hub. Approved users should also acknowledge the specific version(s) of the dataset(s) obtained from the NIH RADx Data Hub.

Funding Opportunity Announcement (FOA) Number: RFA-OD-21-008

NIH Grant or Contract Number(s): 5U01DK132737-02