dbGaP Study Accession: phs003687
NIH Institute/Center: NCATS
RADx Data Program: RADx-UP
DOI: 10.60773/8e0v-pk44
Release Date: 09/13/2024
Study Description: Vulnerable populations including those with medical comorbidities, people living in rural settings and minorities experience significant COVID-19 disparities. Additionally, Hispanics and Blacks are significantly more likely to be infected and hospitalized when compared to White, Non-Hispanics. This study built on RADx-UP Phases I & Phase II work reaching these populations in three racially diverse regions: Houston/Harris County, South Texas, and Northeast Texas to increase SARS-CoV-2 testing, vaccination, and risk mitigation behaviors to reduce COVID-19 morbidity, mortality, and inequities among underserved populations in Texas. The study leveraged the partnerships and resources of the Center for Clinical and Translational Science (CCTS) including long-standing community partnerships. Phase III included mixed methods and community-engaged approaches to inform adaptation of existing (and the development of new) multilevel intervention messages, materials and strategies with a focus on increasing rapid SARS-CoV-2 testing. It also included a broader focus on addressing the social determinants of health (SDOH) and an emphasis on combating misinformation. Innovative elements of the study included testing a novel approach to optimize community engagement that uses real-time data to inform intervention adaptation and implementation, using advances in social computing and machine learning to better understand patterns of misinformation in social media, and using multilevel social network analysis techniques to increase intervention agility, intensity, and reach. This project had three aims: Aim 1: Expand existing sources of population-based COVID-19 surveillance data to quantify infection, testing and vaccination trends in three Texas regions, and use innovative methods to inform and evaluate the proposed interventions. Aim 2: Adapt and implement the adapted multilevel community just-in-time adaptive intervention (MC-JITAI) to increase SARS-CoV-2 testing, mitigation behaviors, and COVID-19 vaccination, among underserved and vulnerable populations in three regions of Texas and conduct; informed by 1) previously collected data (from Phase II), 2) misinformation monitoring studies, and 3) social network information to improve SARS-CoV-2 testing. Aim 3: Evaluate the adapted (in Aim 2) multilevel community intervention (MC-JITAI) and determine how enhancements based on social networks improves SARS-CoV-2 testing and COVID-19 vaccination, in three regions of Texas. Data shared came from Aim 3 where the intervention was evaluated and were baseline measures of the intervention arm.
Principal Investigator: Maria Eulalia Fernandez, PHD
Has Data Files: Yes
Study Domain: Community Outreach Programs; Disease Surveillance; Social Determinants of Health
Data Collection Method: Survey
Keywords: Existing (Legacy)
Study Design: Interventional or Clinical Trial
Multi-Center Study: Yes
Study Sites: The University of Texas Health Science Center Houston, The University of Texas Health Science Center at Tyler
Data Types: Behavioral; Clinical; Psychological; Questionnaire or Survey
Study Start Date: 12/01/2022
Study End Date: 11/30/2024
Species: Human
Estimated Cohort Size: 525
Study Population Focus: Adults; African Americans; Hispanics or Latinos; Older Adults or Elderly; Rural Communities; Underserved or Vulnerable Populations
ClinicalTrials.gov URL: https://clinicaltrials.gov/study/NCT05606003
Acknowledgement Statement: This study was supported through funding, 3U01MD018308-01S1, for the National Center for Advancing Translational Sciences (NCATS) as part of the RADx-UP program. We would like to thank the participants who resided in Northeast Texas, South Texas and Harris County, Texas. We would also like to thank the community partners, investigators, and staff for their dedication to completing the project and improving testing outcomes in underserved communities. Approved users should acknowledge the provision of data access by dbGaP for accession phs003687.v1.p1, and the NIH RADx Data Hub. Approved users should also acknowledge the specific version(s) of the dataset(s) obtained from the NIH RADx Data Hub.
Funding Opportunity Announcement (FOA) Number: RFA-OD-22-006
NIH Grant or Contract Number(s): 3U01TR004355-01S1
Consent/Data Use Limitations: General Research Use
Variable Name | Label |
---|---|
nih_record_id | User ID |
nih_race | What is your race? |
nih_ethnicity | Are you of Hispanic or Latino origin? May include Spanish origin. |
nih_sex | What is your biological sex assigned at birth? |
nih_education | What is the highest level of education you have achieved outside or in the United States? |
nih_employment | Please specify your employment status. |
nih_insurance | What kind of health insurance do you have? |
nih_disability | Do you have a disability, including serious physical or mental conditions, that interfere with your ability to carry out daily activities? |
nih_vape_freq | Vaping Frequency: Do you now use electronic cigarettes every day, some days, rarely, or not at all? |
nih_cig_smoke_freq | Nicotine Frequency: Do you now smoke cigarettes? |
nih_smoking_yn | Do you use any tobacco/nicotine products (including cigarettes, cigars, e-cigarettes, etc)? |
nih_history_smoking | History of Smoking |
nih_alcohol_yn | Alcohol use (Yes or No) |
nih_lifetime_use_alcohol | In your entire life, have you had at least 1 drink of any kind of alcohol, not counting small tastes or sips? (Yes or No) |
nih_alcohol_frequency | How often did you have a drink containing alcohol ? |
nih_asthma | Asthma |
nih_cancer_past_yr | Cancer diagnosis and/or treatment within the past 12 months |
nih_cardiovascular_disease | Cardiovascular disease |
nih_chronic_kidney_disease | Chronic kidney disease |
nih_diabetes | Diabetes |
nih_hypertension | Hypertension |
nih_mental_health_disorder | Mental health disorder |
nih_sickle_cell_disease | Sickle cell disease |
nih_pregnancy | Pregnancy status |
nih_immunocompromised | Immunocompromised condition |
nih_autoimm | Autoimmune disease |
nih_copd | Chronic obstructive pulmonary disease (COPD) |
nih_chronic_lung | Other chronic lung disease |
nih_depression | Depression |
nih_alc_sub_abuse | Alcohol or substance use disorder |
nih_iv_drug_use | Intravenous drug use |
nih_other_chronic_cond | Other chronic condition |
nih_cough | Cough |
nih_fever_chills | Fever or Chills |
nih_diff_breath | Shortness of breath or difficulty breathing |
nih_headache | Headache |
nih_muscle_ache | Muscle ache |
nih_olfactory | New loss of taste or smell |
nih_fatigue | Excessive fatigue |
nih_nausea_vomiting_diarrhea | Nausea, vomiting, or diarrhea |
nih_abdom_pain | Abdominal pain |
nih_skin_rash | Skin rash |
nih_throat_congestion_nose | Sore throat, congestion or runny nose |
nih_other_symp | Other |
nih_health_status | Would you say that (your) health in general is excellent, very good, good, fair, or poor? |
nih_height | What is your height in inches? |
nih_weight | What is your weight in pounds? |
bio_sex_birth_2 | What was your sex assigned at birth on your birth certificate? |
cc_asthma_2 | Asthma |
cc_asud_2 | Alcohol or substance use disorder |
cc_autoimm_2 | Autoimmune disease |
cc_cancer_2 | Cancer diagnosis and/or treatment within the past 12 months |
cc_chronickd_2 | Chronic kidney disease (CKD) |
cc_clung_2 | Other chronic lung disease |
cc_copd_2 | Chronic obstructive pulmonary disease (COPD) |
cc_cvd_2 | Cardiovascular disease (CVD or heart disease) |
cc_depression_2 | Depression |
cc_diabetes_2 | Diabetes |
cc_hypertension_2 | Hypertension (HTN, high blood pressure) |
cc_imm_2 | Immunocompromised condition |
cc_intrav_2 | Intravenous drug use |
cc_otherchroniccond_2 | Other chronic condition |
cc_othermh_2 | Other mental health disorder |
cc_sickle_2 | Sickle Cell Anemia |
covid_abpain_2 | Abdominal Pain |
covid_cough_2 | Cough |
covid_diffbreath_2 | Shortness of breath or difficulty breathing |
covid_fever_2 | Fever or chills |
covid_headache_2 | Headache |
covid_myalgia_2 | Muscle or body aches |
covid_nausea_2 | Feeling sick to your stomach or vomiting, diarrhea |
covid_olfactory_2 | New loss of taste or smell |
covid_other_2 | Other |
covid_runnynose_2 | Sore throat, congestion or runny nose |
covid_skinrash_2 | Skin Rash |
current_employment_status | We would like to know about what you do -- are you working now, looking for work, retired, keeping house, a student, or something else? |
hi_coverage_type | What is the primary kind of health insurance or health care plan that you have now? (Exclude plans that pay for only one type of Service (such as, nursing home care, accidents, family planning, or dental care) and plans that only provide extra cash when hospitalized. ) |
lifetime_use_alcohol | In your entire life, have you had at least 1 drink of any kind of alcohol, not counting small tastes or sips? |
pregnancy_status | Are you currently pregnant? |
race_ethn_hispanic | Are you of Hispanic, Latino, or Spanish origin? |
self_reported_disability | Do you have a disability that interferes with your ability to carry out daily activities? Examples of daily activities include walking, climbing stairs, shopping, balancing a checkbook, bathing or dressing. |
self_reported_height_centimeters | Centimeters |
self_reported_height_feet | Feet |
self_reported_height_inches | Inches |
self_reported_height_meters | Meters |
self_reported_weight_kgs | How much do you weigh without clothes or shoes? If you are currently pregnant, how much did you weigh before your pregnancy? |
self_reported_weight_lbs | How much do you weigh without clothes or shoes? If you are currently pregnant, how much did you weigh before your pregnancy? |
smoker_cur_stat_2 | Do you now smoke cigarettes? |
vaper_cur_stat | Do you now use electronic cigarettes every day, some days, rarely, or not at all? |
agree_followup | - |
alcohol_daysperweek | - |
alcohol_drinksperday | - |
alter_bedrooms | - |
cc_othermh_specify | - |
cc_other_specify | - |
consent_given | - |
consent_ident | - |
consent_recontact | - |
consent_zip_2 | - |
covid_fatique_2 | - |
covid_pandemic_challenges_abod_2 | - |
covid_pandemic_challenges_food_2 | - |
covid_pandemic_challenges_wate_2 | - |
covid_risk | - |
covid_vaccine | - |
cov_pan_chal_hlth_2 | - |
cov_pan_chal_med_2 | - |
cov_pan_chlng_trans_2 | - |
cov_tst_mthd_2 | - |
doses_vaccine | - |
edu_years_of_school | - |
employed_ew | - |
employed_healthcare_2 | - |
family_income | - |
fi_afford_balanced_meals | - |
fi_change_diet | - |
fi_change_diet_frequency | - |
fi_eat_less | - |
fi_food_money_frequency | - |
fi_hungry | - |
flu_vaccinehistind_2 | - |
flu_vaccine_season_3 | - |
gender_identity_term_2 | - |
hi_loss_covid | - |
household_famgen_3 | - |
household_homeless | - |
housing_concerns | - |
howmany_died | - |
howmany_had | - |
isolate_maintain_job | - |
jobloss_covid19_2 | - |
language_english | - |
language_home___1 | - |
language_home___2 | - |
language_home___3 | - |
language_home___4 | - |
language_home___5 | - |
language_home___6 | - |
language_home___7 | - |
language_home___8 | - |
language_home___9 | - |
language_home___90 | - |
language_home___99 | - |
language_pref | - |
positiveyear_covidtest_3 | - |
quarantine_maintain_job | - |
race_ethn_asian_detail_3___1 | - |
race_ethn_asian_detail_3___2 | - |
race_ethn_asian_detail_3___3 | - |
race_ethn_asian_detail_3___4 | - |
race_ethn_asian_detail_3___5 | - |
race_ethn_asian_detail_3___99 | - |
race_ethn_hispanic_detail_2___1 | - |
race_ethn_hispanic_detail_2___2 | - |
race_ethn_hispanic_detail_2___3 | - |
race_ethn_hispanic_detail_2___4 | - |
race_ethn_hispanic_detail_2___5 | - |
race_ethn_hispanic_detail_2___6 | - |
race_ethn_hispanic_detail_2___7 | - |
race_ethn_hispanic_detail_2___99 | - |
race_ethn_islander_detail_2___1 | - |
race_ethn_islander_detail_2___10 | - |
race_ethn_islander_detail_2___11 | - |
race_ethn_islander_detail_2___12 | - |
race_ethn_islander_detail_2___13 | - |
race_ethn_islander_detail_2___14 | - |
race_ethn_islander_detail_2___2 | - |
race_ethn_islander_detail_2___3 | - |
race_ethn_islander_detail_2___4 | - |
race_ethn_islander_detail_2___5 | - |
race_ethn_islander_detail_2___6 | - |
race_ethn_islander_detail_2___7 | - |
race_ethn_islander_detail_2___8 | - |
race_ethn_islander_detail_2___9 | - |
race_ethn_islander_detail_2___99 | - |
race_ethn_race___1 | - |
race_ethn_race___15 | - |
race_ethn_race___2 | - |
race_ethn_race___3 | - |
race_ethn_race___4 | - |
race_ethn_race___5 | - |
race_ethn_race___99 | - |
recentresult_covidtest | - |
recenttest_reason | - |
recenttest_reason_other | - |
recentyear_covidtest_3 | - |
redcap_event_name | - |
redcap_repeat_instance | - |
redcap_repeat_instrument | - |
region | - |
safety_symptoms_1 | - |
safety_symptoms_2 | - |
safety_symptoms_3 | - |
safety_symptoms_4 | - |
safety_symptoms_5 | - |
safety_symptoms_6 | - |
safety_symptoms_7 | - |
safety_symptoms_8 | - |
safety_symptoms_9 | - |
safety_test_1 | - |
safety_test_2 | - |
safety_test_3 | - |
safety_test_4 | - |
safety_test_5 | - |
safety_test_6 | - |
safety_test_7 | - |
safety_test_8 | - |
safety_week_1 | - |
safety_week_2 | - |
safety_week_3 | - |
safety_week_4 | - |
self_reported_health_status_assessment | - |
self_reported_height_coded | - |
self_reported_weight_units_2 | - |
sex_orient_id | - |
smoker_number | - |
smoke_years | - |
stable_housing | - |
study_arm | - |
test_accespay | - |
test_accesseasy_2 | - |
test_accesswhere_2 | - |
test_benefits | - |
tested_for_covid | - |
tested_positive_for_covid | - |
test_future | - |
test_intent_2 | - |
test_intent_antiviral | - |
test_intent_freetest | - |
test_knowing | - |
test_pbenearound_2 | - |
test_pbeneexposed_2 | - |
test_pbenesafe_2 | - |
test_pbenework_2 | - |
test_percvaccuneg_2 | - |
test_percvaccupos_2 | - |
test_protect_people | - |
test_resneg_2___1 | - |
test_resneg_2___2 | - |
test_resneg_2___3 | - |
test_resneg_2___4 | - |
test_resneg_2___99 | - |
test_respos_2___1 | - |
test_respos_2___2 | - |
test_respos_2___3 | - |
test_respos_2___99 | - |
test_se_cost | - |
test_se_donthavetest | - |
test_se_swab | - |
test_se_useathome | - |
trust_institutions_1 | - |
trust_institutions_2 | - |
trust_institutions_3 | - |
trust_institutions_4 | - |
vaccine_concerns_3___1 | - |
vaccine_concerns_3___10 | - |
vaccine_concerns_3___2 | - |
vaccine_concerns_3___3 | - |
vaccine_concerns_3___4 | - |
vaccine_concerns_3___5 | - |
vaccine_concerns_3___6 | - |
vaccine_concerns_3___7 | - |
vaccine_concerns_3___8 | - |
vaccine_concerns_3___9 | - |
vaccine_concerns_3___96 | - |
vaccine_concerns_3___99 | - |
vaccine_reasons_3___1 | - |
vaccine_reasons_3___10 | - |
vaccine_reasons_3___11 | - |
vaccine_reasons_3___2 | - |
vaccine_reasons_3___3 | - |
vaccine_reasons_3___4 | - |
vaccine_reasons_3___5 | - |
vaccine_reasons_3___6 | - |
vaccine_reasons_3___7 | - |
vaccine_reasons_3___8 | - |
vaccine_reasons_3___9 | - |
vaccine_reasons_3___96 | - |
vaccine_reasons_3___99 | - |
vaper_years | - |
weigh_before_pregnant | - |
work_closecont_2 | - |
work_ppe_2 | - |
work_wash_2 | - |