dbGaP Study Accession: phs002786

NIH Institute/Center: NIAMS

RADx Data Program: RADx-UP

Release Date: 08/30/2023

DOI: 10.60773/wtx3-4882

Updated Date: 04/17/2024

Study Description: People living with an autoimmune disease, including those with systemic lupus erythematosus (SLE), have been especially impacted by the COVID-19 pandemic. The purpose of this research project was to identify barriers and facilitators to COVID-19 testing and vaccination among people living with SLE using both qualitative and quantitative methods. This study also evaluated the efficacy of a novel peer-led intervention to enhancing these behaviors among people living with SLE and others in their household/social network using a randomized controlled trial design. The aims of this project were achieved by leveraging an existing patient roster of over 2500 people living with SLE in Birmingham, Alabama. This study also recruited people living with SLE in New Orleans, Louisiana. This research has broader implications for testing/vaccination in clinical populations.

Principal Investigator: Chae, David H

Has Data Files: Yes

Study Domain: Comorbidities; Vaccination Rate/Uptake

Data Collection Method: Survey

Keywords: Barriers to Vaccination; Systemic Lupus Erythematosus (SLE); Autoimmune Disease; Comorbid Populations; Barriers to Testing

Study Design: Case-Control

Multi-Center Study: FALSE

Data Types: Behavioral; Questionnaires/Surveys; Social

Study Start Date: 09/12/2021

Study End Date: 08/31/2023

Species: Human Data

Estimated Cohort Size: 1235

Study Population Focus: African American; Adults; Underserved/Vulnerable Population; Older Adults or Elderly

Acknowledgement Statement: This study was supported through funding, 3R01AR065493-07S2, for the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) as part of the RADx-UP program. Approved users should acknowledge the provision of data access by dbGaP for accession phs002786.v1.p1, and the NIH RADx Data Hub. Approved users should also acknowledge the specific version(s) of the dataset(s) obtained from the NIH RADx Data Hub.

Funding Opportunity Announcement (FOA) Number: PA-11-260

NIH Grant or Contract Number(s): 3R01AR065493-07S2

Consent/Data Use Limitations: General Research Use