dbGaP Study Accession: phs002644

NIH Institute/Center: NCATS

RADx Data Program: RADx-UP

DOI: 10.60773/nxck-yd76

Release Date: 08/31/2023

Updated Date: 04/17/2024

Study Description: Fight COVID MKE used randomized COVID antibody testing in Milwaukee County, Wisconsin to measure the population proportion infected and how this proportion varies over time and with patient demographic and health characteristics. Through partnerships with 20 primary care health centers and with local churches and community agencies to conduct community outreach and engagement, the study oversampled minority, poor, and elderly populations to obtain more precise estimates for these groups. Fight COVID MKE gathered patient-reported health data and leverage extensive data linkages from Wisconsin state data partners to assess the risks of infection progressing to symptoms, hospitalization, ICU stay, or death and to calculate population infection rates as a function of patient and community characteristics. A web-based risk assessment tool was developed in English and Spanish to allow individuals, families, and health care professionals to assess individual risk and advise high-risk individuals on risk mitigation as well as vaccination.

Principal Investigator: Meurer, John Richard

Has Data Files: Yes

Study Domain: Seroprevalence; Serological (Antibody) Testing; Community Outreach Programs

Data Collection Method: Survey

Keywords: COVID-related Mortality Rates; COVID-related Hospitalizations; Infection Rates

Study Design: Interventional/Clinical Trial

Multi-Center Study: TRUE

Study Sites: Froedtert & Medical College of Wisconsin clinics (15); Outreach Community Health Ctr; Progressive Community Health Ctr; Ascension Wisconsin; 16th Street Community Health Ctr; Northwestern University; and William and Mary College

Data Types: Other; Electronic Medical Records; Questionnaires/Surveys

Data Types, Other: Abbott COVID-19 nucleocapsid and spike protein QT lgG antibody test results

Study Start Date: 09/24/2020

Study End Date: 05/31/2025

Species: Human Data

Estimated Cohort Size: 6000

Study Population Focus: Older Adults or Elderly; Lower Socioeconomic Status (SES) Population; Racial and Ethnic Minorities

Publication URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221876/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959409/

Acknowledgement Statement: This study was supported through funding, 5UL1TR001436-10, for the National Center for Advancing Translational Sciences (NCATS) as part of the RADx-UP program. Fight COVID MKE is supported by collaborators from Froedtert & the Medical College of Wisconsin, Northwestern University, Indiana University, William and Mary College, Outreach Community Health Center, Progressive Community Health Center, Sixteenth Street Community Health Center, Ascension Wisconsin, Northcott Neighborhood House, Social Development Commission, Greater Baptist State Convention of WI, Rite-Hite YMCA, and WI Northwest Jurisdiction COGIC. Approved users should acknowledge the provision of data access by dbGaP for accession phs002644.v1.p1, and the NIH RADx Data Hub. Approved users should also acknowledge the specific version(s) of the dataset(s) obtained from the NIH RADx Data Hub.

Funding Opportunity Announcement (FOA) Number: PAR-18-940

NIH Grant or Contract Number(s): 5UL1TR001436-10

Consent/Data Use Limitations: General Research Use