dbGaP Study Accession: phs002565

NIH Institute/Center: NIAAA

RADx Data Program: RADx-rad

Release Date: 06/06/2022

DOI: 10.60773/wd0m-eh53

Updated Date: 12/09/2022

Study Description: This study involved the development of an assay for detecting SARS-CoV-2. Data that included signal for given virus or S protein concentration, as well as binding constants for molecular recognition agents, was generated.

Principal Investigator: Pun, Suzie

Has Data Files: Yes

Study Domain: Medical Device/Tool Development; Virological Testing

Data Collection Method: Molecular (Nucleic Acid/PCR) Testing Device

Keywords: Nanofabrication; Prevention; Secondary Infection; Transmission Process; Viral Detection; Viral Transmission; SARS-CoV-2 Spike Protein; Assay; Affinity; Binding; Biosensing Techniques; Early Diagnosis; Electric Capacitance; Molecular Conformation; Natural Regeneration; Oxidation-Reduction; Pathogen Detection; Sensitivity and Specificity; Signal Transduction; Aptamer Base

Study Design: Device Validation Study

Multi-Center Study: FALSE

Data Types: Immunological; Other

Data Types, Other: Technology development for virus detection

Study Start Date: 12/21/2020

Study End Date: 12/30/2022

Species: Human Data

Estimated Cohort Size: 0

Study Population Focus: N/A

Publication URL: https://pubmed.ncbi.nlm.nih.gov/35972202/; https://pubmed.ncbi.nlm.nih.gov/35532905/; https://pubmed.ncbi.nlm.nih.gov/34328683/; https://pubmed.ncbi.nlm.nih.gov/37206388/

Acknowledgement Statement: This study was supported through funding, 4U01AA029316-02, for the National Institute on Alcohol Abuse and Alcoholism (NIAAA) as part of the RADx-rad program. Approved users should acknowledge the provision of data access by dbGaP for accession phs002565.v1.p1, and the NIH RADx Data Hub. Approved users should also acknowledge the specific version(s) of the dataset(s) obtained from the NIH RADx Data Hub.

Funding Opportunity Announcement (FOA) Number: RFA-OD-20-014

NIH Grant or Contract Number(s): 4U01AA029316-02

Consent/Data Use Limitations: General Research Use